Application of Probiotics in Oral Health
Oral health has a significant impact on the health and quality of life of individuals. The treatment of oral diseases or their complications requires broad-spectrum antibacterial drugs that can trigger gastrointestinal side effects. As an alternative therapy, the role of probiotics in maintaining ecological balance and their effectiveness in normalizing the oral microbiota make them a powerful preventive measure in oral care. Creative Enzymes offers a wide range of probiotic strains or their blends for oral health. At the same time, our advanced research platform provides oral health-related probiotic research and development services for exploring a wider range of probiotic applications.
How Probiotics Affect Oral Health
Many other health problems and diseases are associated with an unhealthy oral microbiome. The oral cavity is equivalent to a micro-ecological environment inhabited by a large number of microorganisms. Infectious diseases develop when factors such as time, diet and immune deficiencies alter this balance and may require complex management due to their multi-microbial nature. Probiotics reduce the harmful effects of pathogenic microorganisms by naturally colonizing the oral cavity. By inhabiting beneficial organisms, the infected areas of the mouth are transformed from an environment rich in inflammatory cytokines to a more benign environment that contributes to general health.
Fig. 1 Potential mechanisms of action of probiotics in oral health and disease. (Saïz, 2021)
Benefits of Probiotics for The Oral Cavity
Probiotics provide many benefits to the mouth, mainly including:
- Improving oral health and reshape the periodontal ecosystem.
- Regulating immune activity.
- Preventing plaque and dental caries.
- Improving bad breath.
Probiotics for Improving Oral Health
Probiotics have a wide range of applications in improving oral health, and there are a large number of probiotic species that can be used to improve oral health or treat oral diseases. The most commonly used species in oral probiotic preparations include Lactobacillus spp, Streptococcus spp, Bifidobacterium spp, etc. Creative Enzymes can provide clients with a wide range of scientifically proven probiotic strains that are safe for use in the oral cavity. The table below describes in detail the categories and specific actions of these strains.
| Applications | Probiotics | Beneficial Effects |
|---|---|---|
| Dental caries | Streptococcus denticola Streptococcus thermophilus Lactobacillus salivarius Lactobacillus rhamnosus Lactobacillus reuteri Lactobacillus casei Lactobacillus paracasei Lactobacillus plantarum Bifidobacteria |
|
| Gingivitis | Lactobacilli Streptococci Bifidobacterium Lactobacillus salivarius Streptococcus salivarius Bifidobacteria Lactobacillus brevis |
|
| Periodontitis | Lactobacillus Lactobacillus brevis Lactobacillus helveticus |
|
| Candidiasis or oral thrush | Lactobacillus rhamnosus Lactobacillus casei Lactobacillus acidophilus Lactobacillus plantarum Streptococcus salivarius |
|
| Bad Breath | Lactobacillu reuteri Lactobacillus salivarius Streptococcus salivarius Enterobacter faecium |
|
Our Capabilities
- Different methods are used to produce anti-caries probiotic formulations.
- Screening and evaluation of new probiotic strains that can be used to improve oral health.
- Developing a variety of dosage forms for oral oral probiotics, including lozenges, mouthwashes or chewable tablets.
- Research of adhesion and customization mechanisms of orally administered probiotics.
Creative Enzymes is a professional and experienced probiotic supplier and service provider. We are committed to using our science to select the ideal strain for our clients for oral health management. To get more information, please contact us and we will be happy to serve your research demands.
Reference
- Saïz, P.; et al. Probiotics in Oral Health and Disease: A Systematic Review. Applied Sciences. 2021, 11(17): 8070.
