Toxicological Assessment of Probiotics
In vivo toxicological assessment of probiotics is a more in-depth and direct study of the safety of probiotics. Creative Enzymes provides a more comprehensive and in-depth analysis of the potential toxicity and mutagenic effects of probiotics through laboratory evaluation and the use of animal models to characterize the in vivo safety of arbitrary probiotics.
The Significance of Toxicological Assessment
The efficacy of new strains must be carefully evaluated prior to incorporation into products and must be evaluated step-by-step through systematic studies to determine if they have the same safety status as conventional organisms at food grade and if probiotics have the potential to enter the industry. Although in vitro tests independent of test animals can be used for initial screening of probiotic safety, they should be combined with in vivo tests to further confirm the effect of any assay.
Toxicological Assessment Services in Creative Enzymes
Creative Enzymes has the test platform and scientific team needed to conduct probiotic toxicology studies and is well positioned to support our clients' research needs and provide professional safety assessments. The toxicological tests we provide are mainly carried out from the following two aspects.
Genotoxicity Tests of Probiotics
Creative Enzymes is using our science to evaluate the possible harmful effects of probiotic cultures on host DNA. Currently, at least three practical tests are commonly used in our laboratory to check the genotoxicity of different probiotics, namely bacterial genetic mutations, chromosomal aberration assays in mammalian cells and micronucleus tests in rodents. As fast and trustworthy genotoxicity tests, they have been successfully developed and applied in our laboratory and has helped our clients to obtain the safety information they need for their probiotic products.
Oral Toxicity Tests of Probiotics
In toxicological assessment, oral toxicity test is an important test to detect the toxicity of a product. Creative Enzymes offers oral toxicity testing methods that follow international standards. In rodent models, we tested the oral toxicity of the probiotics to be tested at a single 14-day (acute), repeated 28-day (subacute) and repeated 90-day (subchronic) doses, respectively. Our experienced laboratory experts, through scientific design and control of details, can provide our clients with detailed toxicological test reports in a short period of time.
Advantages of The Toxicological Assessment We Provided
- Advanced test platform and extensive experience.
- Provide customized assessment test solutions.
- Detailed and reliable toxicological analysis results.
- Competitive prices and on-time delivery.
Creative Enzymes is a professional and experienced probiotic supplier and service provider. We have a professional toxicology testing laboratory with an outstanding laboratory team. For many years, we have been providing testing services for in vivo safety assessment of probiotics with OECD guidelines as the standard. Our capabilities allow us to provide high quality testing services to our global clients. To get more information, please contact us and we will be happy to serve your research demands.
